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From the cobbled streets of Casco Viejo to the sleek skyscrapers of the downtown business district, �ʲ��Բ�����’s cosmopolitan capital has many distinct communities tucked away in its neighborhoods. Panama City is a vibrant hub for history, business and culture – there’s even a rainforest within the city limits.

But where should you base yourself while you're there? Whether you're looking for a party night, locavore treats, family-friendly fun, a slice of colonial history, or the comforts of a contemporary metropolis, you can find it in the following five neighborhoods.

Casco Viejo

Best for architecture, culture and cocktails

Dating back to 1673, compact Casco Viejo is the city’s cultural heart – if you only visit one neighborhood, make it this one! Once a no-go zone, Casco Viejo’s historic, pastel-colored mansions have been restored and now house stylish boutique hotels such as the American Trade Hotel and hip hostels such as .

Casco’s cobbled streets were made for idle wandering. Dip into the incense-scented Iglesia de San José and marvel at its glittering golden altar, or people-watch in the Plaza de la Independencia while slurping an artisan ice cream from .

Discover �ʲ��Բ�����’s unique textile art at the and shop for locally made crafts at the Karavan Gallery, then break for a Geisha coffee – one of the world’s finest and most expensive brews – at the vegan-friendly .

At sundown, head to a rooftop bar – ��á�Գٲ����� is a long-time favorite for a happy-hour cocktail – before some creative Panamanian fusion fare at . Then dance the night away at or Teatro Amador.

Amador

Best for families with kids and world-class museums

To the south of the city, Amador’s namesake causeway juts into the bay, with views over the skyscraping city skyline on one side, and views of supersized ships sailing under the Bridge of the Americas as they enter and exit the Panama Canal on the other.

Created from rocks unearthed during the canal’s construction, this skinny sliver of land has been revitalized and is now a firm favorite with local families and a bridge to the pocket-sized islands of Culebra, Perico, Naos and Flamenco.

Start your journey along the 6km (3.7-mile) causeway by renting a bike from . Drop into the striking, Frank Gehry-designed BioMuseo to learn about �ʲ��Բ�����’s spectacular biodiversity, before stopping off for a seafood feast at the ever-popular on Isla Naos while you drink in the views.

To get active, take to the water with , which caters to paddle boarders of all levels, including people with disabilities. Alternatively, hop on the ferry for the 30-minute ride to volcanic Isla Taboga, the historic Island of Flowers, for a taste of tropical island life (arrange activities at ).

San Francisco

Best for foodies

In the middle of the metropolis, sprawling San Francisco is a favorite stop for local foodies. It’s the home base for many of the city’s top food trucks, and at the city's first designated food truck park, , you'll find everything from sticky ribs to well-stuffed tacos, craft beer to cocktails, and live music to artisan market stalls.

For more tasty treats, food-truck-turned-restaurant serves up flavorful meat and veggie burgers. There’s also a branch of serving its popular menu of affordable and filling Panamanian fare. Meanwhile, caffeine lovers can sample the country’s best coffee at Cafe Unido.

You can burn off those extra calories at the alfresco gyms and jogging trails of Parque Recreativo Omar, one of the city’s green lungs, which hosts free open-air concerts and art exhibitions in summer.

���Գ�ó��

Best for green spaces and contemporary art

Part of the former Canal Zone, the tranquil residential neighborhood of ���Գ�ó�� is home to the city’s highest point, Cerro ���Գ�ó��, which rises to 200m (650ft) above sea level, with an iconic Panama flag – said to be larger than a basketball court – fluttering at its peak.

Set your alarm and hit the paved trail to the summit, winding up slopes thick with rainforest vegetation and sprinkled with tropical flowers. Keep your eyes peeled for slow-moving sloths, diminutive Geoffroy’s tamarin monkeys and raccoon-like coatis. Alongside wildlife encounters, you’ll be rewarded with panoramic views over the tiled rooftops of Casco and downtown’s sparkling steel-and-glass towers.

For an art fix, stop off at the imposing Panama Canal Administration Building on the hill’s western slope to see the powerful murals depicting the epic struggle to build the canal. Then head east to the Museo de Arte Contemporáneo (MAC Panamá), which showcases local and Latin American art, with an interesting line-up of temporary exhibitions.

Punta Pacifica

Best for glitzy hotels and designer stores

Punta Pacifica is one of the city’s newest and most exclusive neighborhoods, where eye-wateringly expensive high-rise condos stand shoulder-to-shoulder on a petite peninsula overlooking the ocean. There are top-notch shopping and international restaurants to match, but alongside designer stores, the Multiplaza Mall has around 50 eateries to suit all budgets.

For sea views, walk down to Cinta Costera, which hugs the coast as far as Casco Viejo and runs parallel to Avenida Balboa. Every Sunday morning, the beltway is transformed into a ���������DZ�� (cycleway), so hire a bike and join the throng of riders. Behind Punta Pacific are the lively, multicultural barrios of Obarrio and El Cangrejo, offering more wallet-friendly accommodation.

If you’re not staying at the sail-shaped , you can get a taste of the showstopping views at , said to be the highest rooftop bar in Central America. Alternatively, try to bag yourself a luxe Airbnb, where you can watch the twinkling lights of ships as they wait to enter the canal.